Tom Williams


263 results

Sickle Cell Anemia and Its Phenotypes.Williams TN, Thein SL
Annu Rev Genomics Hum Genet, (2018). 19:113-147

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children.Gilchrist JJ, Mentzer AJ, Rautanen A, Pirinen M, Mwarumba S, Njuguna P, Mturi N, Wellcome Trust Case-Control Consortium, Kenyan Bacteraemia Study Group, Williams TN, Scott JAG, Hill AVS
Proc Natl Acad Sci U S A, (2018). 115:E3601-E3603

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, Molyneux ME, Knight JC, Spencer CCA, Williams TN, MacLennan CA, Scott JAG, Hill AVS
Nat Commun, (2018). 9:1014

Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya.Brent AJ, Nyundo C, Langat J, Mulunda C, Wambua J, Bauni E, Sande J, Park K, Williams TN, Newton CRJ, Levin M, Scott JAG, Kids TB Study Group
Emerg Infect Dis, (2018). 24:514-523

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.Taylor WR, Naw HK, Maitland K, Williams TN, Kapulu M, D'Alessandro U, Berkley JA, Bejon P, Okebe J, Achan J, Amambua AN, Affara M, Nwakanma D, van Geertruyden JP, Mavoko M, Lutumba P, Matangila J, Brasseur P, Piola P, Randremanana R, Lasry E, Fanello C, Onyamboko M, Schramm B, Yah Z, Jones J, Fairhurst RM, Diakite M, Malenga G, Molyneux M, Rwagacondo C, Obonyo C, Gadisa E, Aseffa A, Loolpapit M, Henry MC, Dorsey G, John C, Sirima SB, Barnes KI, Kremsner P, Day NP, White NJ, Mukaka M
BMC Med, (2018). 16:11

Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.McGann PT, Williams TN, Olupot-Olupot P, Tomlinson GA, Lane A, Luis Reis da Fonseca J, Kitenge R, Mochamah G, Wabwire H, Stuber S, Howard TA, McElhinney K, Aygun B, Latham T, Santos B, Tshilolo L, Ware RE, REACH Investigators
Am J Hematol, (2018). 93:537-545

The clinical epidemiology of sickle cell anemia In Africa.Macharia AW, Mochamah G, Uyoga S, Ndila CM, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN
Am J Hematol, (2018). 93:363-370

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait.Etyang AO, Wandabwa CK, Kapesa S, Muthumbi E, Odipo E, Wamukoya M, Ngomi N, Haregu T, Kyobutungi C, Williams TN, Makale J, Macharia A, Cruickshank JK, Smeeth L, Scott JAG
Am J Epidemiol, (2018). 187:199-205

Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System [version 1; referees: 1 approved, 1 approved with reservations].Nyundo C, Doyle AM, Walumbe D, Otiende M, Kinuthia M, Amadi D, Jibendi B, Mochamah G, Kihuha N, Williams TN, Ross DA, Bauni E
Wellcome Open Res, (2017). 2:

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia.Maitland K, Kiguli S, Opoka RO, Olupot-Olupot P, Engoru C, Njuguna P, Bandika V, Mpoya A, Bush A, Williams TN, Grieve R, Sadique Z, Fraser J, Harrison D, Rowan K
Wellcome Open Res, (2017). 2:100

No Evidence that Knops Blood Group Polymorphisms Affect Complement Receptor 1 Clustering on Erythrocytes.Swann OV, Harrison EM, Opi DH, Nyatichi E, Macharia A, Uyoga S, Williams TN, Rowe JA
Sci Rep, (2017). 7:17825

Subphenotypes of sickle cell disease in Africa.Piel FB, Williams TN
Blood, (2017). 130:2157-2158

Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction.Mogeni P, Williams TN, Omedo I, Kimani D, Ngoi JM, Mwacharo J, Morter R, Nyundo C, Wambua J, Nyangweso G, Kapulu M, Fegan G, Bejon P
J Infect Dis, (2017). 216:1091-1098

Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children.Mugyenyi CK, Elliott SR, Yap XZ, Feng G, Boeuf P, Fegan G, Osier FFH, Fowkes FJI, Avril M, Williams TN, Marsh K, Beeson JG
J Infect Dis, (2017). 216:887-898

The frequency and severity of epistaxis in children with sickle cell anaemia in eastern Uganda: a case-control study.Nardo-Marino A, Williams TN, Olupot-Olupot P
BMC Hematol, (2017). 17:14

Prevalence of Inherited Hemoglobin Disorders and Relationships with Anemia and Micronutrient Status among Children in Yaounde and Douala, Cameroon.Engle-Stone R, Williams TN, Nankap M, Ndjebayi A, Gimou MM, Oyono Y, Tarini A, Brown KH, Green R
Nutrients, (2017). 9:

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa.Omedo I, Mogeni P, Bousema T, Rockett K, Amambua-Ngwa A, Oyier I, Stevenson CJ, Baidjoe AY, de Villiers EP, Fegan G, Ross A, Hubbart C, Jeffreys A, Williams TN, Kwiatkowski D, Bejon P
Wellcome Open Res, (2017). 2:10

Resistance to malaria through structural variation of red blood cell invasion receptors.Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP, Malaria Genomic Epidemiology Network
Science, (2017). 356:

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With alpha(+)Thalassemia.Etyang AO, Khayeka-Wandabwa C, Kapesa S, Muthumbi E, Odipo E, Wamukoya M, Ngomi N, Haregu T, Kyobutungi C, Tendwa M, Makale J, Macharia A, Cruickshank JK, Smeeth L, Scott JA, Williams TN
J Am Heart Assoc, (2017). 6:

High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda.Olupot-Olupot P, Engoru C, Uyoga S, Muhindo R, Macharia A, Kiguli S, Opoka RO, Akech S, Ndila C, Nyeko R, Mtove G, Nteziyaremye J, Chebet M, George EC, Babiker AG, Gibb DM, Williams TN, Maitland K
Clin Infect Dis, (2017). 64:939-946