Tom Williams
263 results
The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia.Muriuki JM, Mentzer AJ, Band G, Gilchrist JJ, Carstensen T, Lule SA, Goheen MM, Joof F, Kimita W, Mogire R, Cutland CL, Diarra A, Rautanen A, Pomilla C, Gurdasani D, Rockett K, Mturi N, Ndungu FM, Scott JAG, Sirima SB, Morovat A, Prentice AM, Madhi SA, Webb EL, Elliott AM, Bejon P, Sandhu MS, Hill AVS, Kwiatkowski DP, Williams TN, Cerami C, Atkinson SH
Sci Adv, (2019). 5:eaaw0109
The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: a prospective cohort study.Uyoga S, Macharia AW, Mochamah G, Ndila CM, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Otiende M, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Maitland K, Scott JAG, Williams TN
Lancet Glob Health, (2019). 7:e1458-e1466
Transfusion Volume for Children with Severe Anemia in Africa.Maitland K, Olupot-Olupot P, Kiguli S, Chagaluka G, Alaroker F, Opoka RO, Mpoya A, Engoru C, Nteziyaremye J, Mallewa M, Kennedy N, Nakuya M, Namayanja C, Kayaga J, Uyoga S, Kyeyune Byabazaire D, M'Baya B, Wabwire B, Frost G, Bates I, Evans JA, Williams TN, Saramago Goncalves P, George EC, Gibb DM, Walker AS, Tract Group
N Engl J Med, (2019). 381:420-431
Immediate Transfusion in African Children with Uncomplicated Severe Anemia.Maitland K, Kiguli S, Olupot-Olupot P, Engoru C, Mallewa M, Saramago Goncalves P, Opoka RO, Mpoya A, Alaroker F, Nteziyaremye J, Chagaluka G, Kennedy N, Nabawanuka E, Nakuya M, Namayanja C, Uyoga S, Kyeyune Byabazaire D, M'Baya B, Wabwire B, Frost G, Bates I, Evans JA, Williams TN, George EC, Gibb DM, Walker AS, Tract Group
N Engl J Med, (2019). 381:407-419
Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya.Njuguna P, Maitland K, Nyaguara A, Mwanga D, Mogeni P, Mturi N, Mohammed S, Mwambingu G, Ngetsa C, Awuondo K, Lowe B, Adetifa I, Scott JAG, Williams TN, Atkinson S, Osier F, Snow RW, Marsh K, Tsofa B, Peshu N, Hamaluba M, Berkley JA, Newton CRJ, Fondo J, Omar A, Bejon P
BMC Med, (2019). 17:124
Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort.Muthui MK, Mogeni P, Mwai K, Nyundo C, Macharia A, Williams TN, Nyangweso G, Wambua J, Mwanga D, Marsh K, Bejon P, Kapulu MC
Wellcome Open Res, (2019). 4:66
Effect of strikes by health workers on mortality between 2010 and 2016 in Kilifi, Kenya: a population-based cohort analysis.Ong'ayo G, Ooko M, Wang'ondu R, Bottomley C, Nyaguara A, Tsofa BK, Williams TN, Bejon P, Scott JAG, Etyang AO
Lancet Glob Health, (2019). 7:e961-e967
Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study.Hammitt LL, Etyang AO, Morpeth SC, Ojal J, Mutuku A, Mturi N, Moisi JC, Adetifa IM, Karani A, Akech DO, Otiende M, Bwanaali T, Wafula J, Mataza C, Mumbo E, Tabu C, Knoll MD, Bauni E, Marsh K, Williams TN, Kamau T, Sharif SK, Levine OS, Scott JAG
Lancet, (2019). 393:2146-2154
Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study.Etyang AO, Kapesa S, Odipo E, Bauni E, Kyobutungi C, Abdalla M, Muntner P, Musani SK, Macharia A, Williams TN, Cruickshank JK, Smeeth L, Scott JAG
J Am Heart Assoc, (2019). 8:e011771
Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa.Uyoga S, Mpoya A, Olupot-Olupot P, Kiguli S, Opoka RO, Engoru C, Mallewa M, Kennedy N, M'Baya B, Kyeyune D, Wabwire B, Bates I, Gibb DM, Walker AS, George EC, Williams TN, Maitland K
Vox Sang, (2019). 114:340-348
The indirect health effects of malaria estimated from health advantages of the sickle cell trait.Uyoga S, Macharia AW, Ndila CM, Nyutu G, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN
Nat Commun, (2019). 10:856
Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis.Silaba M, Ooko M, Bottomley C, Sande J, Benamore R, Park K, Ignas J, Maitland K, Mturi N, Makumi A, Otiende M, Kagwanja S, Safari S, Ochola V, Bwanaali T, Bauni E, Gleeson F, Deloria Knoll M, Adetifa I, Marsh K, Williams TN, Kamau T, Sharif S, Levine OS, Hammitt LL, Scott JAG
Lancet Glob Health, (2019). 7:e337-e346
Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE, REACH Investigators
N Engl J Med, (2019). 380:121-131
The population dynamics of hemoglobins A, A2, F and S in the context of the hemoglobinopathies HbS and alpha-thalassemia in Kenyan infants.Macharia AW, Uyoga S, Ndila C, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Atkinson S, Williams TN
Haematologica, (2019). 104:e184-e186
Iron Status and Associated Malaria Risk Among African Children.Muriuki JM, Mentzer AJ, Kimita W, Ndungu FM, Macharia AW, Webb EL, Lule SA, Morovat A, Hill AVS, Bejon P, Elliott AM, Williams TN, Atkinson SH
Clin Infect Dis, (2019). 68:1807-1814
Evaluation of the diagnostic accuracy and cost of different methods for the assessment of severe anaemia in hospitalised children in Eastern Uganda.Olupot-Olupot P, Prevatt N, Engoru C, Nteziyaremye J, Amorut D, Chebet M, Senyondo T, Ongodia P, Ndila CM, Williams TN, Maitland K
Wellcome Open Res, (2018). 3:130
Sickle Cell and alpha+-Thalassemia Traits Influence the Association between Ferritin and Hepcidin in Rural Kenyan Children Aged 14-26 Months.Byrd KA, Williams TN, Lin A, Pickering AJ, Arnold BF, Arnold CD, Kiprotich M, Dentz HN, Njenga SM, Rao G, Colford JM, Null C, Stewart CP
J Nutr, (2018). 148:1903-1910
Coverage and timeliness of vaccination and the validity of routine estimates: Insights from a vaccine registry in Kenya.Adetifa IMO, Karia B, Mutuku A, Bwanaali T, Makumi A, Wafula J, Chome M, Mwatsuma P, Bauni E, Hammitt LL, Mataza C, Tabu C, Kamau T, Williams TN, Scott JAG
Vaccine, (2018). 36:7965-7974
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepulveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN, Malaria GENConsortium
Lancet Haematol, (2018). 5:e333-e345
Two complement receptor one alleles have opposing associations with cerebral malaria and interact with alpha(+)thalassaemia.Opi DH, Swann O, Macharia A, Uyoga S, Band G, Ndila CM, Harrison EM, Thera MA, Kone AK, Diallo DA, Doumbo OK, Lyke KE, Plowe CV, Moulds JM, Shebbe M, Mturi N, Peshu N, Maitland K, Raza A, Kwiatkowski DP, Rockett KA, Williams TN, Rowe JA
Elife, (2018). 7: