Eunice Nduati

Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya.Fwambah L, Andisi C, Streatfield C, Bromell R, Hare J, Esbjornsson J, Ndung'u T, Sanders EJ, Hassan AS, Nduati E
Front Immunol, (2023). 14:1283559

Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay.Fernandez N, Hayes P, Makinde J, Hare J, King D, Xu R, Rehawi O, Mezzell AT, Kato L, Mugaba S, Serwanga J, Chemweno J, Nduati E, Price MA, Osier F, Ochsenbauer C, Yue L, Hunter E, Gilmour J
Front Immunol, (2022). 13:1029029

Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro.Nyagwange J, Kutima B, Mwai K, Karanja HK, Gitonga JN, Mugo D, Sein Y, Wright D, Omuoyo DO, Nyiro JU, Tuju J, Nokes DJ, Agweyu A, Bejon P, Ochola-Oyier LI, Scott JAG, Lambe T, Nduati E, Agoti C, Warimwe GM
Int J Infect Dis, (2022). 127:11-16

Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination.Nduati EW, Gorman MJ, Sein Y, Hermanus T, Yuan D, Oyaro I, Muema DM, Ndung'u T, Alter G, Moore PL
AIDS, (2021). 35:1895-1905

A Novel Sample Selection Approach to Aid the Identification of Factors That Correlate With the Control of HIV-1 Infection.Makinde J, Nduati EW, Freni-Sterrantino A, Streatfield C, Kibirige C, Dalel J, Black SL, Hayes P, Macharia G, Hare J, McGowan E, Abel B, King D, Joseph S, Iavi Protocol C Investigators, Hunter E, Sanders EJ, Price M, Gilmour J
Front Immunol, (2021). 12:634832

Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans.Sutton HJ, Aye R, Idris AH, Vistein R, Nduati E, Kai O, Mwacharo J, Li X, Gao X, Andrews TD, Koutsakos M, Nguyen THO, Nekrasov M, Milburn P, Eltahla A, Berry AA, Kc N, Chakravarty S, Sim BKL, Wheatley AK, Kent SJ, Hoffman SL, Lyke KE, Bejon P, Luciani F, Kedzierska K, Seder RA, Ndungu FM, Cockburn IA
Cell Rep, (2021). 34:108684

Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype.Aye R, Sutton HJ, Nduati EW, Kai O, Mwacharo J, Musyoki J, Otieno E, Wambua J, Bejon P, Cockburn IA, Ndungu FM
Eur J Immunol, (2020). 50:1187-1194

Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants.Musimbi ZD, Rono MK, Otieno JR, Kibinge N, Ochola-Oyier LI, de Villiers EP, Nduati EW
Sci Rep, (2019). 9:18124

Symptom-based Scoring for Acute Human Immunodeficiency Virus.Sanders EJ, Kigoro A, Thiong'o A, Nduati E, Graham SM
Clin Infect Dis, (2019). 69:736-737

Cytomegalovirus viraemia is associated with poor growth and T-cell activation with an increased burden in HIV-exposed uninfected infants.Garcia-Knight MA, Nduati E, Hassan AS, Nkumama I, Etyang TJ, Hajj NJ, Gambo F, Odera D, Berkley JA, Rowland-Jones SL, Urban B
AIDS, (2017). 31:1809-1818

Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children.Muema DM, Macharia GN, Olusola BA, Hassan AS, Fegan GW, Berkley JA, Urban BC, Nduati EW
PLoS One, (2017). 12:e0175570

The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".Bediako Y, Ngoi JM, Nyangweso G, Wambua J, Opiyo M, Nduati EW, Bejon P, Marsh K, Ndungu FM
BMC Med, (2016). 14:143

HIV-Exposed Uninfected Infants Show Robust Memory B-Cell Responses in Spite of a Delayed Accumulation of Memory B Cells: an Observational Study in the First 2 Years of Life.Nduati EW, Nkumama IN, Gambo FK, Muema DM, Knight MG, Hassan AS, Jahangir MN, Etyang TJ, Berkley JA, Urban BC
Clin Vaccine Immunol, (2016). 23:576-85

Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan Infants.Garcia-Knight MA, Nduati E, Hassan AS, Gambo F, Odera D, Etyang TJ, Hajj NJ, Berkley JA, Urban BC, Rowland-Jones SL
PLoS One, (2015). 10:e0143043

Outcomes of prevention of mother to child transmission of the human immunodeficiency virus-1 in rural Kenya--a cohort study.Nduati EW, Hassan AS, Knight MG, Muema DM, Jahangir MN, Mwaringa SL, Etyang TJ, Rowland-Jones S, Urban BC, Berkley JA
BMC Public Health, (2015). 15:1008

Control of Viremia Enables Acquisition of Resting Memory B Cells with Age and Normalization of Activated B Cell Phenotypes in HIV-Infected Children.Muema DM, Macharia GN, Hassan AS, Mwaringa SM, Fegan GW, Berkley JA, Nduati EW, Urban BC
J Immunol, (2015). 195:1082-91

10-valent pneumococcal non-typeable Haemophilus influenzae protein-D conjugate vaccine (PHiD-CV) induces memory B cell responses in healthy Kenyan toddlers.Muema DM, Nduati EW, Uyoga M, Bashraheil M, Scott JA, Hammitt LL, Urban BC
Clin Exp Immunol, (2015). 181:297-305

HIV-exposed uninfected children: a growing population with a vulnerable immune system?.Afran L, Garcia Knight M, Nduati E, Urban BC, Heyderman RS, Rowland-Jones SL
Clin Exp Immunol, (2014). 176:11-22

The plasma concentration of the B cell activating factor is increased in children with acute malaria.Nduati E, Gwela A, Karanja H, Mugyenyi C, Langhorne J, Marsh K, Urban BC
J Infect Dis, (2011). 204:962-70

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.Nduati EW, Ng DH, Ndungu FM, Gardner P, Urban BC, Langhorne J
PLoS One, (2010). 5:e15007