Williams TN

Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa.Uyoga S, Mpoya A, Olupot-Olupot P, Kiguli S, Opoka RO, Engoru C, Mallewa M, Kennedy N, M'Baya B, Kyeyune D, Wabwire B, Bates I, Gibb DM, Walker AS, George EC, Williams TN, Maitland K
Vox Sang, (2019). 114:340-348

The indirect health effects of malaria estimated from health advantages of the sickle cell trait.Uyoga S, Macharia AW, Ndila CM, Nyutu G, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN
Nat Commun, (2019). 10:856

Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis.Silaba M, Ooko M, Bottomley C, Sande J, Benamore R, Park K, Ignas J, Maitland K, Mturi N, Makumi A, Otiende M, Kagwanja S, Safari S, Ochola V, Bwanaali T, Bauni E, Gleeson F, Deloria Knoll M, Adetifa I, Marsh K, Williams TN, Kamau T, Sharif S, Levine OS, Hammitt LL, Scott JAG
Lancet Glob Health, (2019). 7:e337-e346

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, Lane A, Aygun B, Stuber SE, Latham TS, McGann PT, Ware RE, REACH Investigators
N Engl J Med, (2019). 380:121-131

The population dynamics of hemoglobins A, A2, F and S in the context of the hemoglobinopathies HbS and alpha-thalassemia in Kenyan infants.Macharia AW, Uyoga S, Ndila C, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Atkinson S, Williams TN
Haematologica, (2019). 104:e184-e186

Iron Status and Associated Malaria Risk Among African Children.Muriuki JM, Mentzer AJ, Kimita W, Ndungu FM, Macharia AW, Webb EL, Lule SA, Morovat A, Hill AVS, Bejon P, Elliott AM, Williams TN, Atkinson SH
Clin Infect Dis, (2019). 68:1807-1814

Evaluation of the diagnostic accuracy and cost of different methods for the assessment of severe anaemia in hospitalised children in Eastern Uganda.Olupot-Olupot P, Prevatt N, Engoru C, Nteziyaremye J, Amorut D, Chebet M, Senyondo T, Ongodia P, Ndila CM, Williams TN, Maitland K
Wellcome Open Res, (2018). 3:130

Sickle Cell and alpha+-Thalassemia Traits Influence the Association between Ferritin and Hepcidin in Rural Kenyan Children Aged 14-26 Months.Byrd KA, Williams TN, Lin A, Pickering AJ, Arnold BF, Arnold CD, Kiprotich M, Dentz HN, Njenga SM, Rao G, Colford JM, Null C, Stewart CP
J Nutr, (2018). 148:1903-1910

Coverage and timeliness of vaccination and the validity of routine estimates: Insights from a vaccine registry in Kenya.Adetifa IMO, Karia B, Mutuku A, Bwanaali T, Makumi A, Wafula J, Chome M, Mwatsuma P, Bauni E, Hammitt LL, Mataza C, Tabu C, Kamau T, Williams TN, Scott JAG
Vaccine, (2018). 36:7965-7974

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepulveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN, Malaria GENConsortium
Lancet Haematol, (2018). 5:e333-e345

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with alpha(+)thalassaemia.Opi DH, Swann O, Macharia A, Uyoga S, Band G, Ndila CM, Harrison EM, Thera MA, Kone AK, Diallo DA, Doumbo OK, Lyke KE, Plowe CV, Moulds JM, Shebbe M, Mturi N, Peshu N, Maitland K, Raza A, Kwiatkowski DP, Rockett KA, Williams TN, Rowe JA
Elife, (2018). 7:

Sickle Cell Anemia and Its Phenotypes.Williams TN, Thein SL
Annu Rev Genomics Hum Genet, (2018). 19:113-147

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children.Gilchrist JJ, Mentzer AJ, Rautanen A, Pirinen M, Mwarumba S, Njuguna P, Mturi N, Wellcome Trust Case-Control Consortium, Kenyan Bacteraemia Study Group, Williams TN, Scott JAG, Hill AVS
Proc Natl Acad Sci U S A, (2018). 115:E3601-E3603

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, Molyneux ME, Knight JC, Spencer CCA, Williams TN, MacLennan CA, Scott JAG, Hill AVS
Nat Commun, (2018). 9:1014

Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya.Brent AJ, Nyundo C, Langat J, Mulunda C, Wambua J, Bauni E, Sande J, Park K, Williams TN, Newton CRJ, Levin M, Scott JAG, Kids TB Study Group
Emerg Infect Dis, (2018). 24:514-523

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.Taylor WR, Naw HK, Maitland K, Williams TN, Kapulu M, D'Alessandro U, Berkley JA, Bejon P, Okebe J, Achan J, Amambua AN, Affara M, Nwakanma D, van Geertruyden JP, Mavoko M, Lutumba P, Matangila J, Brasseur P, Piola P, Randremanana R, Lasry E, Fanello C, Onyamboko M, Schramm B, Yah Z, Jones J, Fairhurst RM, Diakite M, Malenga G, Molyneux M, Rwagacondo C, Obonyo C, Gadisa E, Aseffa A, Loolpapit M, Henry MC, Dorsey G, John C, Sirima SB, Barnes KI, Kremsner P, Day NP, White NJ, Mukaka M
BMC Med, (2018). 16:11

Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa.McGann PT, Williams TN, Olupot-Olupot P, Tomlinson GA, Lane A, Luis Reis da Fonseca J, Kitenge R, Mochamah G, Wabwire H, Stuber S, Howard TA, McElhinney K, Aygun B, Latham T, Santos B, Tshilolo L, Ware RE, REACH Investigators
Am J Hematol, (2018). 93:537-545

The clinical epidemiology of sickle cell anemia In Africa.Macharia AW, Mochamah G, Uyoga S, Ndila CM, Nyutu G, Makale J, Tendwa M, Nyatichi E, Ojal J, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN
Am J Hematol, (2018). 93:363-370

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait.Etyang AO, Wandabwa CK, Kapesa S, Muthumbi E, Odipo E, Wamukoya M, Ngomi N, Haregu T, Kyobutungi C, Williams TN, Makale J, Macharia A, Cruickshank JK, Smeeth L, Scott JAG
Am J Epidemiol, (2018). 187:199-205

Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System [version 1; referees: 1 approved, 1 approved with reservations].Nyundo C, Doyle AM, Walumbe D, Otiende M, Kinuthia M, Amadi D, Jibendi B, Mochamah G, Kihuha N, Williams TN, Ross DA, Bauni E
Wellcome Open Res, (2017). 2: