Ndungu FM

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.Pieper K, Tan J, Piccoli L, Foglierini M, Barbieri S, Chen Y, Silacci-Fregni C, Wolf T, Jarrossay D, Anderle M, Abdi A, Ndungu FM, Doumbo OK, Traore B, Tran TM, Jongo S, Zenklusen I, Crompton PD, Daubenberger C, Bull PC, Sallusto F, Lanzavecchia A
Nature, (2017). 548:597-601

The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".Bediako Y, Ngoi JM, Nyangweso G, Wambua J, Opiyo M, Nduati EW, Bejon P, Marsh K, Ndungu FM
BMC Med, (2016). 14:143

Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models.Ndungu FM, Marsh K, Fegan G, Wambua J, Nyangweso G, Ogada E, Mwangi T, Nyundo C, Macharia A, Uyoga S, Williams TN, Bejon P
BMC Med, (2015). 13:183

Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children.Olotu A, Clement F, Jongert E, Vekemans J, Njuguna P, Ndungu FM, Marsh K, Leroux-Roels G, Bejon P
PLoS One, (2014). 9:e115126

Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion.Illingworth J, Butler NS, Roetynck S, Mwacharo J, Pierce SK, Bejon P, Crompton PD, Marsh K, Ndungu FM
J Immunol, (2013). 190:1038-47

Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya.Ibison F, Olotu A, Muema DM, Mwacharo J, Ohuma E, Kimani D, Marsh K, Bejon P, Ndungu FM
PLoS One, (2012). 7:e52939

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E.Ndungu FM, Mwacharo J, Kimani D, Kai O, Moris P, Jongert E, Vekemans J, Olotu A, Bejon P
PLoS One, (2012). 7:e52870

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.Ndungu FM, Olotu A, Mwacharo J, Nyonda M, Apfeld J, Mramba LK, Fegan GW, Bejon P, Marsh K
Proc Natl Acad Sci U S A, (2012). 109:8247-52

High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections.Weiss GE, Ndungu FM, McKittrick N, Li S, Kimani D, Crompton PD, Marsh K, Pierce SK
J Immunol Methods, (2012). 375:68-74

Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study.Muema DK, Ndungu FM, Kinyanjui SM, Berkley JA
Malar J, (2011). 10:55

Apicomplexa: Malaria.Lamb TJ, Ndungu FM
Immunity to Parasitic Infections, (2011). :

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.Nduati EW, Ng DH, Ndungu FM, Gardner P, Urban BC, Langhorne J
PLoS One, (2010). 5:e15007

Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells.Stephens R, Ndungu FM, Langhorne J
Parasite Immunol, (2009). 31:20-31

Immunity to malaria: more questions than answers.Langhorne J, Ndungu FM, Sponaas AM, Marsh K
Nat Immunol, (2008). 9:725-32

CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway.Ndungu FM, Sanni L, Urban B, Stephens R, Newbold CI, Marsh K, Langhorne J
J Immunol, (2006). 176:5504-12

Regulation of immune response by Plasmodium-infected red blood cells.Ndungu FM, Urban BC, Marsh K, Langhorne J
Parasite Immunol, (2005). 27:373-84

Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity.Bull PC, Pain A, Ndungu FM, Kinyanjui SM, Roberts DJ, Newbold CI, Marsh K
J Infect Dis, (2005). 192:1119-26

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area.Dorfman JR, Bejon P, Ndungu FM, Langhorne J, Kortok MM, Lowe BS, Mwangi TW, Williams TN, Marsh K
J Infect Dis, (2005). 191:1623-30

Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2.Ndungu FM, Bull PC, Ross A, Lowe BS, Kabiru E, Marsh K
Parasite Immunol, (2002). 24:77-82