Malaria Evolution

Malaria Evolution and Epidemiology
We are studying which genes of the malaria parasite allow it to adapt to its environment, particularly with regard to the intensity of transmission and host immunity.  This will help us understand how the parasite might evolve in response to vaccines and drugs.  This includes studies of the transcriptomes of parasites taken from areas under different transmission intensities.  We are also working to develop reliable epidemiological, genetic and statistical approaches to identify hotspots of malaria transmission, the aim being to guide malaria control teams to target their interventions for maximum cost-effectiveness and impact.

Investigators : Investigators: Martin Rono, Peter Bull, Vandana Thathy, Philip Bejon