Children’s Oxygen Administration Strategies Trial

The Kenya Paediatric Association (KPA), in partnership with the KEMRI Wellcome Trust Research Programme held a seminar on Thursday 5th at the four point Sheraton hotel in Nairobi. The main speaker, a Professor of Tropical Paediatric Infectious Diseases at Imperial College, Dr Kathryn Maitland was presenting her research on child mortality. Those in attendance were nurses, medical officers and paediatricians.

Her research on Children Oxygenation Saturation Strategies Trials (COAST) examines how oxygen saturation threshold should be targeted and administered. In Africa, the clinical syndrome of pneumonia remains the leading cause of morbidity and mortality in children in the post-neonatal period. It therefore represents a significant burden on in-patient services. The targeted use of oxygen and simple, non-invasive methods of respiratory support may be a highly cost-effective means of improving outcome, but both the optimal oxygen saturation threshold which results in benefit and the best strategy for delivery are yet to be tested in adequately powered randomised controlled trials. COAST was designed to address the poor outcomes of children in sub-Saharan Africa