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Use WPMLHealth System & Research Ethics
Biography
Primus is a public health specialist and bioethicist, with an interest in the ethics of controlled human infection studies and health policy and systems research in LMICs. Primus joined the programme in July 2018 as a Mid-Level Social Scientist (Senior Postdoctoral Researcher) from the Karolinska Institute, Sweden, where he served as a researcher and lecturer with the Department of Public Health Sciences from March 2016 – April 2018. Prior to that he served as a doctoral researcher with the Peace Research Institute Oslo (PRIO), where he worked on health systems in conflict-affected settings. Primus holds a PhD in International Health from the University of Oslo, Norway, an MPH (Public health and Research ethics) from the University of Pretoria, South Africa, and an M.Sc. (Medical Microbiology/Parasitology) from the University of Buea, Cameroon.
Current Work
He leads a social science controlled human malaria infection (CHMI) study imbedded within ongoing and planned CHMI studies at the KEMRI-Wellcome Trust Research Programme in kilifi, Kenya. Working with a team of scientists and social scientists, he employs empirical ethics approaches to understand the social and ethical implications of conducting such studies in a LMIC setting, with the goal of strengthening policy and practice.Collaborations
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Project Research
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Publications
Fourth Controlled Human Infection Model (CHIM) meeting - CHIMs in endemic countries, May 22-23, 2023.
Kapulu, M., Manda-Taylor, L., Balasingam, S., Means, G., Ayiro Malungu, M., Bejon, P., Chi, P. C., Chiu, C., Church, E. C., Correa-Oliveira, R., Day, N., Durbin, A., Egesa, M., Emerson, C., Jambo, K., Mathur, R., Metzger, W., Mumba, N., Nazziwa, W., Olotu, A., Rodgers, J., Sinyiza, F., Talaat, K., Kamerling, I., Weller, C., Baay, M., Neels, P.
Biologicals, (2024). :101747
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
Odera, D. O., Tuju, J., Mwai, K., Nkumama, I. N., Fürle, K., Chege, T., Kimathi, R., Diehl, S., Musasia, F. K., Rosenkranz, M., Njuguna, P., Hamaluba, M., Kapulu, M. C., Frank, R., Osier, F. H. A., Abdi, A. I., Chi, P. C., de Laurent, Z., Jao, I., Kamuya, D., Kamuyu, G., Makale, J., Murungi, L., Musyoki, J., Muthui, M., Mwacharo, J., Kariuki, S., Mwanga, D., Mwongeli, J., Ndungu, F., Njue, M., Nyangweso, G., Kimani, D., Ngoi, J. M., Musembi, J., Ngoto, O., Otieno, E., Ooko, M., Shangala, J., Wambua, J., Mohammed, K. S., Omuoyo, D., Mosobo, M., Kibinge, N., Kinyanjui, S., Bejon, P., Lowe, B., Marsh, K., Marsh, V., Abebe, Y., Billingsley, P. F., Sim, B. K. L., Hoffman, S. L., James, E. R., Richie, T. L., Audi, A., Olewe, F., Oloo, J., Ongecha, J., Ongas, M. O., Koskei, N., Bull, P. C., Hodgson, S. H., Kivisi, C., Imwong, M., Murphy, S. C., Ogutu, B., Tarning, J., Winterberg, M., Williams, T. N.
Sci Transl Med, (2023). 15:eabn5993
A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses.
Ngwenya, N., Ilo Van Nuil, J., Nyirenda, D., Chambers, M., Cheah, P. Y., Seeley, J., Chi, P., Mafuleka, L., Nkosi, B., Kamuya, D., Davies, A., Schneiders, M. L., Mumba, N., Dlamini, S., Desmond, N., Marsh, V., Rippon, D., Parker, M., Molyneux, S.
Wellcome Open Res, (2022). 7:48
'Labouring' on the frontlines of global health research: mapping challenges experienced by frontline workers in Africa and Asia.
Nkosi, B., Van Nuil, J. I., Nyirenda, D., Chi, P. C., Schneiders, M. L.
Glob Public Health, (2022). 17:1-11
Ethical considerations around volunteer payments in a malaria human infection study in Kenya: an embedded empirical ethics study.
Chi, P. C., Owino, E. A., Jao, I., Bejon, P., Kapulu, M., Marsh, V., Kamuya, D.
BMC Med Ethics, (2022). 23:46
"We should be at the table together from the beginning": perspectives on partnership from stakeholders at four research institutions in sub-Saharan Africa.
Voller, S., Chitalu, C. M., Nyondo-Mipando, A. L., Opobo, T., Bangirana, C. A., Thorogood, N., Schellenberg, J., Chi, P.
Int J Equity Health, (2022). 21:111
Barriers and facilitators of and strategies for successful community engagement in infectious disease clinical trials in low‐ and middle‐income countries.
Schmidt, B. M., Späth, C., van Pinxteren, M., Chi, P. C., Wiysonge, C. S., Oliver, J., Colvin, C. J.
Cochrane Database of Systematic Reviews, (2022). 8:
Undertaking Community Engagement for a Controlled Human Malaria Infection Study in Kenya: Approaches and Lessons Learnt.
Mumba, N., Njuguna, P., Chi, P., Marsh, V., Awuor, E., Hamaluba, M., Mauncho, C., Mwalukore, S., Masha, J., Mwangoma, M., Kalama, B., Alphan, H., Wambua, J., Bejon, P., Kamuya, D., Kapulu, M. C.
Front Public Health, (2022). 10:793913
Government regulation of private health insurance.
Motaze, N. V., Chi, P. C., Ongolo-Zogo, P., Ndongo, J. S., Wiysonge, C. S.
Cochrane Database Syst Rev, (2021). 2:CD011512
Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders.
Chi, P. C., Owino, E. A., Jao, I., Olewe, F., Ogutu, B., Bejon, P., Kapulu, M., Kamuya, D., Marsh, V., CHMI-SIKA Study Team
Trials, (2021). 22:494