Kathryn Maitland, an author of a study protocol published on Wellcome Open Research, talks about gastroenteritis and the importance of the Phase II GASTRO trial to monitor children’s responses to rehydration therapy.
Gastroenteritis is the second biggest cause of death in children under 5 years, after acute respiratory illnesses, with the vast majority occurring in low resource settings including sub-Saharan Africa. A large multi-continent study of gastroenteritis (GEMS) found that children hospitalised with gastroenteritis with dehydration are eight and half more times more likely to die than other causes, with one third of these deaths occurring within a week of hospitalisation. This indicates that current management strategies are not working in practice. read more