Isabella completed her PhD in 2006 at the Liverpool School of Tropical Medicine and Hygiene on a Gates Malaria Partnership scholarship, in molecular and cell biology of Plasmodium falciparum. The project focused on the molecular characterization of the endocytic marker Rab5 in the parasite. She then joined the KEMRI Wellcome Trust Research Programme (KWTRP) on a 3 year postdoctoral research position working on studies of natural selection in Plasmodium falciparum merozoite antigen genes, with Prof Kevin Marsh and Dr David Conway. Under this project she was involved in establishing the capillary sequencing facility at the unit and began to develop her career in the molecular epidemiology of malaria. She was awarded a 2 year re-entry grant from the Malaria Capacity Development Consortium (MCDC) in 2009 to conduct a longitudinal study on the genetic diversity of merozoite antigens. In 2012 she extended her interest to the genetic diversity of known human erythrocyte receptors involved in the invasion of the merozoite and is conducting this work under an 18 month MCDC Initiative award. She is also conducting research on the temporal variation in malaria drug resistance markers in collaboration with Dr. Colin Sutherland at the London School of Hygiene and Tropical Medicine. She is now based at the Centre of Biotechnology and Bioinformatics (CEBIB), University of Nairobi (UON), since 2011. Isabella is currently developing her next research grant application on the molecular dynamic interactions between merozoite antigens, immunity and invasion.