Dr Charles Agoti graduated from the University of Nairobi in 2006 with a BSc (Chemistry and Biochemistry) and shortly after joined the KEMRI-Wellcome Trust Kilifi for a research internship. For more than 10 years Charles has continued to work within the KEMRI-WT programme with his primary research focus being the molecular epidemiology of respiratory viruses in coastal Kenya. Both his MSc and PhD research projects focused on large-scale sequencing and bioinformatic analysis of respiratory syncytial virus (RSV) to illuminate on local evolutionary and transmission patterns to suggest new ways of infection control. His work has been very insightful in understanding RSV repeat infections, origin of strains that seed local RSV epidemics and utility of full-genome analysis in detailed understanding of respiratory virus transmission in households and overall community. Recently Charles received funding from the IDeAL (Initiave to Develop African Research Leaders) programme (under Mid-Career Research Fellowship) to extend his work to Viral Diarrhoea Genomics Pre- and Post-Rotavirus Vaccination in Kenya to Understand Virus Source, Transmission Patterns and Vaccine Impact.
Charles is currently involved in 4 key projects (i) studying the transmission pathways of respiratory virus diseases (SPReD) in Kenya and Africa (ii) viral diarrhoea genomics pre- and post-rotavirus vaccination in Kenya to understand virus source, transmission patterns and vaccine impact, (iii) stool extracts archiving project (SEAP) and (iv) transmission patterns of arboviruses in coastal Kenya.
Agoti, C. N., Otieno, J. R., Ngama, M., Mwihuri, A. G., Medley, G. F., Cane, P. A., Nokes, D. J.
J Virol. 2015; : 11630-42
Agoti, C. N., Otieno, J. R., Munywoki, P. K., Mwihuri, A. G., Cane, P. A., Nokes, D. J., Kellam, P., Cotten, M.
Journal of Virology. 2015; : 3444-54
Agoti, C. N., Mwihuri, A. G., Sande, C. J., Onyango, C. O., Medley, G. F., Cane, P. A., Nokes, D. J.
J Infect Dis. 2012; : 1532-41