Ambrose studied medicine at the University of Nairobi and holds a Master of Science in Epidemiology from the London School of Hygiene and Tropical Medicine. He is currently a PhD student, registered at the University of Warwick. Since joining the Child and Newborn Health Group in January 2009, his research work has spanned a range of disciplines including systematic reviews, clinical trials and evaluation of quality of care within hospitals. During the revision of the Kenyan paediatric clinical practice guidelines in 2010, Ambrose was involved in evidence synthesis and preparation of presentations for important clinical questions addressed at the guideline development meeting. More recently, he led the design of a large ongoing multi-Centre randomized controlled trial comparing antibiotic treatments for childhood pneumonia on which he is the principal investigator. As a member of the core team brought together by the government of Kenya to drive the Kenya Action Plan for the Prevention and Control of Pneumonia (KAPP), Ambrose is also actively involved in advocacy on how best to implement prevention and care for childhood pneumonia in Kenya and campaigning for greater attention to be paid to this major childhood killer.