Ambrose is a Kenyan paediatrician and epidemiologist, based at the KEMRI-Wellcome Trust Research Programme in Nairobi. Working closely with the Kenya Ministry of Health in 2009, his early research involved conducting systematic reviews for a national exercise to adapt the World Health Organization pneumonia clinical practice guidelines using the GRADE methodology. Following this, Ambrose was invited to support similar exercises in Uganda and Rwanda. More recently, he was the principal investigator on a large pragmatic clinical trial comparing antibiotic treatments for childhood pneumonia. The findings of this study contributed towards a recent major revision in the Kenyan guidelines, and are likely to eventually influence practice in the region. As a member of the core team brought together by the Government of Kenya to drive the Kenya Action Plan for the Prevention and Control of Pneumonia (KAPP), Ambrose is also actively involved in advocacy on how best to implement prevention and care for childhood pneumonia in Kenya and campaigning for greater attention to be paid to this major childhood killer.
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